Scientific Colloquium
June 15, 2016, 3:30 p.m.
SPECIAL LOCATION: Building 33, Room
H114
RAFAEL
CASELLAS
NATIONAL INSTITUTES OF
HEALTH
"CRISPR: Enabling the 21st
Century Biological Revolution"
CRISPR, an acronym for
Clustered Regularly Interspaced Short Palindromic Repeats, is a
novel genetic engineering tool that permits biologist to easily
edit genetic information in any living organism. Although only
recently discovered, this technique has been refined so rapidly
that it is currently being used around the world to eliminate
incurable diseases, modify foods, and even create designer
humans. The lecture will give an overview of the historical
background, most exciting uses, and ethical issues surrounding
CRISPR.
About the Speaker:
Rafael Casellas is the head of the Genomics
& Immunity laboratory at the National Institutes of
Health in Bethesda. He received a Ph.D. in 2002 from the
Rockefeller University in New York, where he studied
molecular immunology with Howard Hughes investigator
Michel Nussenzweig. In 2003, following a one year post-doc
at Caltech under Novel Laureate David Baltimore, Dr.
Casellas was hired by the NIH, where he is currently a
senior investigator and branch chief. His research focuses
on the nuclear events that drive lymphocyte activation and
tumor development. To achieve its goals, the Casellas
laboratory makes use of mouse genetics, high-resolution
microscopy, genomics, bioinformatics, and CRISPR editing
tools.
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